En la esclerosis sistémica, el esófago se afecta en un 90%, seguido de los tramos anorrectal (%), gástrico ( 70%), colon (%) e intestino delgado. La esclerodermia es un relativamente infrecuente enfermedad reumática autoinmunitaria que afecta la piel y otros órganos del cuerpo. La esclerosis sistémica es una enfermedad autoinmune del tejido conectivo, que se caracteriza por un depósito excesivo de tejido colágeno y otros.

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Tratamiento de la esclerosis sistémica | Reumatología Clínica

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Endothelial cell apoptosis in systemic sclerosis is induced by antibody-dependent cell-mediated cytotoxicity via CD